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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
1995-12-28
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pubmed:abstractText |
Clonal disorders of large granular lymphocytes (LGL) of either CD3- (NK cell) or CD 3+ (T-cell) phenotype have been described. B-cell malignancies such as hairy cell leukemia and non-Hodgkin's lymphoma have been observed in association with the T-cell type of LGL leukemia. Here we report the occurrence of LGL lymphocytosis in four patients with Hodgkin's disease. Immunophenotyping studies showed that these LGL were CD 3- in three patients and CD3+ in the other. LGL were polyclonally expanded in both patients in whom clonality could be assessed.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD3,
http://linkedlifedata.com/resource/pubmed/chemical/Bleomycin,
http://linkedlifedata.com/resource/pubmed/chemical/Dacarbazine,
http://linkedlifedata.com/resource/pubmed/chemical/Doxorubicin,
http://linkedlifedata.com/resource/pubmed/chemical/Etoposide,
http://linkedlifedata.com/resource/pubmed/chemical/Mechlorethamine,
http://linkedlifedata.com/resource/pubmed/chemical/Prednisone,
http://linkedlifedata.com/resource/pubmed/chemical/Procarbazine,
http://linkedlifedata.com/resource/pubmed/chemical/Vinblastine,
http://linkedlifedata.com/resource/pubmed/chemical/Vincristine
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0361-8609
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
50
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
234-6
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:7485096-Antigens, CD3,
pubmed-meshheading:7485096-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:7485096-Bleomycin,
pubmed-meshheading:7485096-Dacarbazine,
pubmed-meshheading:7485096-Doxorubicin,
pubmed-meshheading:7485096-Etoposide,
pubmed-meshheading:7485096-Hodgkin Disease,
pubmed-meshheading:7485096-Humans,
pubmed-meshheading:7485096-Killer Cells, Natural,
pubmed-meshheading:7485096-Lymphocytes,
pubmed-meshheading:7485096-Lymphocytosis,
pubmed-meshheading:7485096-Mechlorethamine,
pubmed-meshheading:7485096-Neoplasm Staging,
pubmed-meshheading:7485096-Prednisone,
pubmed-meshheading:7485096-Procarbazine,
pubmed-meshheading:7485096-T-Lymphocytes,
pubmed-meshheading:7485096-Vinblastine,
pubmed-meshheading:7485096-Vincristine
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pubmed:year |
1995
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pubmed:articleTitle |
Lymphocytosis of large granular lymphocytes in patients with Hodgkin's disease.
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pubmed:affiliation |
Veteran's Administration Hospital, Syracuse, NY 13210, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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