Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
1995-12-22
|
pubmed:abstractText |
Myositis linked to HTLV-1 is unfrequent. Over a period of 8 years, 14 patients with inflammatory myopathy were diagnosed in Martinique. Seven were seropositive for HTLV 1 antibody; the clinical and pathological data of whom are presented herein. Five patients presented with polymyositis, two with dermatomyositis. All seven patients had extra-muscular clinical features including neuropathy (4/7) and myelopathy (6/7), resulting in a quite peculiar clinical picture. Muscle biopsy showed a neurogenic process combined with myositic changes in 3/7 patients. Corticotherapy led to dramatic improvement in only one case, but with no sustained effect. HTLV 1 may be considered the etiological agent of this form of dermato-polymyositis, characterized by a clearly distinctive clinico-pathological picture, and a poor response to corticotherapy. As in the case of tropical spastic paraparesis/HTLV 1 associated myelopathy, careful assessment of non-steroidal therapy is now warranted.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Sep
|
pubmed:issn |
0001-6314
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
92
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
206-12
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:7484073-Adult,
pubmed-meshheading:7484073-Aged,
pubmed-meshheading:7484073-Biopsy,
pubmed-meshheading:7484073-Child,
pubmed-meshheading:7484073-Dermatomyositis,
pubmed-meshheading:7484073-Female,
pubmed-meshheading:7484073-Follow-Up Studies,
pubmed-meshheading:7484073-HTLV-I Infections,
pubmed-meshheading:7484073-Humans,
pubmed-meshheading:7484073-Male,
pubmed-meshheading:7484073-Martinique,
pubmed-meshheading:7484073-Middle Aged,
pubmed-meshheading:7484073-Muscle, Skeletal,
pubmed-meshheading:7484073-Neurologic Examination,
pubmed-meshheading:7484073-Paraparesis, Tropical Spastic,
pubmed-meshheading:7484073-Polymyositis,
pubmed-meshheading:7484073-Prednisone,
pubmed-meshheading:7484073-Treatment Failure
|
pubmed:year |
1995
|
pubmed:articleTitle |
Clinical characteristics of HTLV-1 associated dermato-polymyositis. Seven cases from Martinique.
|
pubmed:affiliation |
Department of Neurology, University Hospital of Fort-de-France, Martinique, French West Indies.
|
pubmed:publicationType |
Journal Article,
Case Reports,
Research Support, Non-U.S. Gov't
|