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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1995-11-30
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pubmed:abstractText |
Lifelong Tibetan residents of 3658 m ventilate as much and have hypoxic and hypercapnic ventilatory responsiveness as least as great as acclimatized newcomers, and likely greater than lifelong North or South American high-altitude residents. To determine whether Tibetans residing at altitudes > 3658 m maintained similar levels of ventilation, hypoxic and hypercapnic ventilatory responses, we transported 20 lifelong residents of > or = 4400 m to 3658 m for comparison with 27 similarly-aged male Tibetan residents of 3658 m. At 3658 m, the 4400 m compared with the 3658 m Tibetans had similar levels of minute ventilation and arterial O2 saturation, higher respiratory quotients but lower hypoxic ventilatory responses. We conclude that Tibetan residents of > or = 4400 m ventilate as much as Tibetan residents of 3658 m despite an altitude-associated blunting of their hypoxic ventilatory responses. Thus, factors other than hypoxic ventilatory chemosensitivity are likely to be important contributors to resting ventilation among Tibetan high altitude residents.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0034-5687
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
100
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
223-30
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pubmed:dateRevised |
2009-11-11
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pubmed:meshHeading |
pubmed-meshheading:7481111-Adult,
pubmed-meshheading:7481111-Altitude,
pubmed-meshheading:7481111-Anoxia,
pubmed-meshheading:7481111-Carbon Dioxide,
pubmed-meshheading:7481111-Hemoglobins,
pubmed-meshheading:7481111-Humans,
pubmed-meshheading:7481111-Hypercapnia,
pubmed-meshheading:7481111-Male,
pubmed-meshheading:7481111-Oxygen,
pubmed-meshheading:7481111-Oxygen Consumption,
pubmed-meshheading:7481111-Respiration,
pubmed-meshheading:7481111-Tibet,
pubmed-meshheading:7481111-Vital Capacity
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pubmed:year |
1995
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pubmed:articleTitle |
Hypoxic ventilatory responses in Tibetan residents of 4400 m compared with 3658 m.
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pubmed:affiliation |
Department of Anthropology, University of Colorado at Denver 80217-3364, USA.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, Non-P.H.S.
|