Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
8983
|
pubmed:dateCreated |
1995-11-27
|
pubmed:abstractText |
Hepatitis viruses A, B, C, D, and E have not accounted for all cases of hepatitis, hence "non A-E" agent(s) might be implicated. A set of new viruses (GBV-A, -B, and -C) whose genomes have been sequenced, are being investigated as possible causes of non A-E hepatitis. We investigated six cases of fulminant hepatitis of unknown aetiology for the presence of GBV-C genome in their serum, and three showed positive signals by semi-nested PCR using primers derived from the NS3/helicase region. Nucleotide sequence analyses confirmed these signals to be derived from a GBV-C sequence. The results suggest the importance of GBV-C in the aetiology of fulminant hepatitis.
|
pubmed:commentsCorrections | |
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
AIM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Oct
|
pubmed:issn |
0140-6736
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
28
|
pubmed:volume |
346
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1131-2
|
pubmed:dateRevised |
2004-11-17
|
pubmed:meshHeading |
pubmed-meshheading:7475605-Adolescent,
pubmed-meshheading:7475605-Adult,
pubmed-meshheading:7475605-Aged,
pubmed-meshheading:7475605-Base Sequence,
pubmed-meshheading:7475605-Female,
pubmed-meshheading:7475605-Flavivirus,
pubmed-meshheading:7475605-Flavivirus Infections,
pubmed-meshheading:7475605-Genome, Viral,
pubmed-meshheading:7475605-Hepatitis, Viral, Human,
pubmed-meshheading:7475605-Humans,
pubmed-meshheading:7475605-Male,
pubmed-meshheading:7475605-Middle Aged,
pubmed-meshheading:7475605-Molecular Sequence Data,
pubmed-meshheading:7475605-Polymerase Chain Reaction,
pubmed-meshheading:7475605-RNA, Viral
|
pubmed:year |
1995
|
pubmed:articleTitle |
Detection of the GBV-C hepatitis virus genome in serum from patients with fulminant hepatitis of unknown aetiology.
|
pubmed:affiliation |
Department of Gastroenterology, Fujigaoka Hospital, Showa University School of Medicine, Yokohama, Japan.
|
pubmed:publicationType |
Journal Article
|