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pubmed:abstractText |
The ability of a partially purified rat ileum peroxidase to synthetize PGE2 and PGF2 alpha from arachidonic acid was researched. The enzyme preparation, when incubated anaerobically with H2O2 and arachidonic acid, produced a compound extractable with ethyl acetate which showed on TLC the same Rf as authentic PGE2. This compound, after elution from the gel, was able to contract the rat strip fundus preparation.
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