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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
7
|
pubmed:dateCreated |
1981-4-13
|
pubmed:abstractText |
Human serum contains small amounts of free and esterified cholesterol precursors, such as lanosterol and other methyl sterols. Incubating the serum for 24 h at room temperature without and with different additions of free methyl sterols was not followed by any detectable esterification of these sterols during the subsequent 24 h incubation period, though the amount of cholesterol esters was markedly increased. [3H]dihydrolanosterol added to serum was not esterified in any lipoprotein fraction either, whereas the [14C]cholesterol added was found to be esterified during the 24 h incubation period. The lack of methyl sterol esterification in vitro suggests that these sterols are not proper substrates for serum lecithin: cholesterol acyltransferase and that esterified serum methyl sterols originate from tissues.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
0036-5513
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
40
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
671-4
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading | |
pubmed:year |
1980
|
pubmed:articleTitle |
A lack of esterification of lanosterol and other methyl sterols in human serum in vitro.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|