Linked Life Data

7465125

Source:http://linkedlifedata.com/resource/pubmed/id/7465125

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1981-4-24
pubmed:abstractText
Because of the involvement of prostaglandins in the labor mechanism, it was hypothesized that elevated prostaglandin levels would presage preterm deliveries. A comparison of plasma 13,14-dihydro-15-ketoprostaglandin F2 alpha (PGFM) levels was made between pregnant patients who eventually delivered at term (N = 22) and those who delivered preterm (N = 17). Maternal blood was collected from each patient at approximately 1-week intervals between 16 and 40 weeks' gestation and during labor. Mixed cord blood was also obtained at delivery. PGFM was measured in plasma by radioimmunoassay. Plasma PGFM concentrations did not vary throughout pregnancy. PGFM concentrations did increase during labor, and the highest levels were found in cord blood at delivery. Mean PGFM levels during labor and in cord blood were not significantly different between the preterm and term groups. In 1 preterm delivery patient the PGFM concentration during labor was higher than that of all other patients, including those who delivered at term. Excluding this patient, preterm labor PGFM concentrations were significantly lower (P less than .05) than those at term. In general, the study provides evidence that most cases of preterm labor are not characterized by elevated prostaglandin levels.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0029-7844
pubmed:author
pubmed:issnType
Print
pubmed:volume
57
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
203-6
pubmed:dateRevised
2009-10-26
pubmed:meshHeading
pubmed:year
1981
pubmed:articleTitle
Plasma prostaglandin in pregnant women with term and preterm deliveries.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, U.S. Gov't, P.H.S.