Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1981-4-21
pubmed:abstractText
The long-term effect of level of protein intake on calcium metabolism, renal function and renal acid excretion was determined during a 75-day metabolic study. Six women consumed a diet containing either 46 or 123 g protein for 60 days; they then consumed the alternate diet for 15 days. Calcium, phosphorus and magnesium intakes were maintained constant at 500, 900 and 350 mg, respectively, throughout the 75-day study. Urinary calcium was remarkably constant with time at both levels of protein intake but was approximately twice as high when the 123 g protein diet was consumed. Level of protein intake had no effect on calcium absorption; the increase in urinary calcium found when the high protein diet was given, therefore, caused a markedly negative calcium balance. Glomerular filtration rate (GFR) and renal acid excretion were higher and fractional renal tubular reabsorption of calcium was lower when the high protein diet was given. The hypercalciuria caused by the high protein intake was due primarily to the decrease in fractional tubular reabsorption of calcium and, to a lesser extent, to the increase in GFR. Neither GFR, fractional renal tubular reabsorption of calcium nor any of the components of renal acid excretion exhibited any tendency to change with time over the 60-day experimental period.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0022-3166
pubmed:author
pubmed:issnType
Print
pubmed:volume
111
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
244-51
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1981
pubmed:articleTitle
Long-term effects of level of protein intake on calcium metabolism in young adult women.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't