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rdf:type |
|
|
lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
1981-4-24
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pubmed:abstractText |
The methionine residues in bovine growth hormone were chemically modified wih chloramine-T at pH 7.4 using different chloramine-T methionine molar ratios. Methionine 4 was shown to be the most reactive followed in decreasing order by methionines 148, 123 and 178. With a 50-fold molar excess of chloramine-T over methionine almost full oxidation of all the methionine residues was achieved. The oxidation of the four residues of methionine does not change the growth promoting activity of the hormone.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0367-8377
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
16
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
299-305
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:7461909-Amino Acid Sequence,
pubmed-meshheading:7461909-Animals,
pubmed-meshheading:7461909-Cattle,
pubmed-meshheading:7461909-Chloramines,
pubmed-meshheading:7461909-Circular Dichroism,
pubmed-meshheading:7461909-Growth Hormone,
pubmed-meshheading:7461909-Indicators and Reagents,
pubmed-meshheading:7461909-Methionine,
pubmed-meshheading:7461909-Oxidation-Reduction,
pubmed-meshheading:7461909-Peptide Fragments,
pubmed-meshheading:7461909-Protein Conformation,
pubmed-meshheading:7461909-Tosyl Compounds,
pubmed-meshheading:7461909-Trypsin
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pubmed:year |
1980
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pubmed:articleTitle |
Oxidation of methionine residues in bovine growth hormone by chloramine-T.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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