Linked Life Data

7460791

Source:http://linkedlifedata.com/resource/pubmed/id/7460791

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4-6
pubmed:dateCreated
1981-4-24
pubmed:abstractText
Choline (Ch) uptake in the iris of the chick has been characterized from 4 1/2 days of incubation to 1 year of age, in conjunction with an electron microscopic ultrastructural study of the innervation of the iris. Uptake has been shown to constitute an early and reliable biochemical marker for the presence of innervation in target organs. The characteristics of Ch uptake, including Na+ and temperature dependence and inhibitor sensitivity, change during development, and the Vmax increases steadily while the Km does not vary significantly during the period of study. The relationships among uptake and other cholinergic functions also change with development of the iris. Acetylcholine (ACh) and Ch uptake but not Ch levels appear to develop together, while cholinergic enzyme activities follow a developmental course more closely related to neurotransmission. The significance of these findings in relation to proposed regulatory relationships in cholinergic biosynthetic mechanisms in discussed.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0378-5866
pubmed:author
pubmed:issnType
Print
pubmed:volume
3
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
185-98
pubmed:dateRevised
2007-7-17
pubmed:meshHeading
pubmed:year
1980
pubmed:articleTitle
Development and aging of cholinergic synapses. III. Choline uptake in the developing iris of the chick.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't