Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
1981-4-24
|
pubmed:abstractText |
Phorbol esters can induce differentiation into macrophage-like cells in the two human myeloid leukaemia cell lines HL-60 and KG-1. We investigated the requirement for DNA synthesis in this differentiation process. We found that phorbol ester-induced differentiation of blast cells into cells with the morphologic, histochemical, and phagocytic characteristics of macrophages did not require 3H-thymidine incorporation. Our results indicate that phorbol ester induced macrophage differentiation does not require DNA synthesis.
|
pubmed:grant | |
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Mar
|
pubmed:issn |
0007-1048
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
47
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
479-83
|
pubmed:dateRevised |
2007-11-14
|
pubmed:meshHeading |
pubmed-meshheading:7459283-Cell Differentiation,
pubmed-meshheading:7459283-Cell Line,
pubmed-meshheading:7459283-DNA,
pubmed-meshheading:7459283-Humans,
pubmed-meshheading:7459283-Leukemia,
pubmed-meshheading:7459283-Macrophages,
pubmed-meshheading:7459283-Phagocytosis,
pubmed-meshheading:7459283-Phorbol Esters,
pubmed-meshheading:7459283-Phorbols
|
pubmed:year |
1981
|
pubmed:articleTitle |
Induction by phorbol esters of macrophage differentiation in human leukaemia cell lines does not require cell division.
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
|