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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
|
| pubmed:dateCreated |
1981-4-13
|
| pubmed:abstractText |
The pharmacokinetics and analgesic effect of i.v. ketamine in doses of 125 microgram kg-1 and 250 microgram kg-1 were determined in five healthy volunteers. Analgesia was measured with the submaximal effort tourniquet test. Both doses of ketamine prolonged the period of pain-free ischaemic exercise while the plasma ketamine concentration was greater than 100 ng ml-1. Ketamine was distributed rapidly (T 1/2 alpha = 17 min). The elimination half-life was 186 min.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jan
|
| pubmed:issn |
0007-0912
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
53
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
27-30
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:7459184-Adult,
pubmed-meshheading:7459184-Analgesia,
pubmed-meshheading:7459184-Half-Life,
pubmed-meshheading:7459184-Humans,
pubmed-meshheading:7459184-Injections, Intravenous,
pubmed-meshheading:7459184-Ketamine,
pubmed-meshheading:7459184-Kinetics,
pubmed-meshheading:7459184-Male
|
| pubmed:year |
1981
|
| pubmed:articleTitle |
Pharmacokinetics and analgesic effect of ketamine in man.
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|