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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1981-3-27
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pubmed:abstractText |
Bronchoalveolar lavage was performed in 47 volunteers: 19 nonsmokers and 28 smokers. Total protein, albumin, immunoglobulins G and A, and carcinoembryonic antigen (CEA) were measured in the concentrated lavage effluent. Although a significant increase (p < 0.001) in the ratio of CEA to total protein recovered from the group of smokers was found, this increase primarily reflected the greater increase that occurred in a subgroup of 7 smokers. However, the increases in lavage CEA correlated weakly (p = 0.096) with smoking history in pack-years, and not at all with plasma CEA concentrations. Results regarding the number of cells recovered and immunoglobulin-to-albumin concentration ratios in these subjects were similar to those reported by others. Thus, CEA was increased in the lavage fluid of a subgroup of otherwise normal young smokers. It is possible that CEA might serve as a useful indicator of future airway disease in certain young smokers.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0003-0805
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
123
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
29-31
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:7458083-Adult,
pubmed-meshheading:7458083-Albumins,
pubmed-meshheading:7458083-Bronchi,
pubmed-meshheading:7458083-Carcinoembryonic Antigen,
pubmed-meshheading:7458083-Cell Count,
pubmed-meshheading:7458083-Female,
pubmed-meshheading:7458083-Humans,
pubmed-meshheading:7458083-Immunoglobulin A,
pubmed-meshheading:7458083-Macrophages,
pubmed-meshheading:7458083-Male,
pubmed-meshheading:7458083-Middle Aged,
pubmed-meshheading:7458083-Pulmonary Alveoli,
pubmed-meshheading:7458083-Smoking,
pubmed-meshheading:7458083-Therapeutic Irrigation
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pubmed:year |
1981
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pubmed:articleTitle |
Quantitation of carcinoembryonic antigen in the lung lining fluid of normal smokers and nonsmokers.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|