| pubmed-article:7453713 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:7453713 | lifeskim:mentions | umls-concept:C0026809 | lld:lifeskim |
| pubmed-article:7453713 | lifeskim:mentions | umls-concept:C0439660 | lld:lifeskim |
| pubmed-article:7453713 | lifeskim:mentions | umls-concept:C0040715 | lld:lifeskim |
| pubmed-article:7453713 | lifeskim:mentions | umls-concept:C0039593 | lld:lifeskim |
| pubmed-article:7453713 | lifeskim:mentions | umls-concept:C0022885 | lld:lifeskim |
| pubmed-article:7453713 | lifeskim:mentions | umls-concept:C1522702 | lld:lifeskim |
| pubmed-article:7453713 | lifeskim:mentions | umls-concept:C0599718 | lld:lifeskim |
| pubmed-article:7453713 | lifeskim:mentions | umls-concept:C0599813 | lld:lifeskim |
| pubmed-article:7453713 | lifeskim:mentions | umls-concept:C0599893 | lld:lifeskim |
| pubmed-article:7453713 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:7453713 | pubmed:dateCreated | 1981-3-27 | lld:pubmed |
| pubmed-article:7453713 | pubmed:abstractText | The status of the heritable-translocation test in mice with respect to its usefulness in practical testing was evaluated by using information available in the open literature. A total of 47 reports were evaluated; 29 were judged to contain adequate information to classify whether or not a given chemical induced heritable translocations. Heritable-translocation data were available for 32 compounds; data were not adequate for 15 compounds. Of the remaining 17 compounds, clear-cut determination of positive or negative effects was made for 14 compounds, while data for 3 compounds were only suggestive of either negative or positive effects. 10 chemicals have been shown to induce heritable translocations. These chemicals are either direct or indirect alkylating agents. The heritable-translocation test needs to be improved before it can be used in wide-scale practical testing. The most important question is whether or not historical controls can be used in tests for significance; the cost of concurrent controls is prohibitive. There is a need to standardize methods used in testing laboratories with respect to the size of error involved in classifying translocation heterozygotes and the power of the test. There is also a need to study in the effectiveness of non-alkylating clastogens in inducing heritable translocations in mice. | lld:pubmed |
| pubmed-article:7453713 | pubmed:language | eng | lld:pubmed |
| pubmed-article:7453713 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:7453713 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:7453713 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:7453713 | pubmed:month | Sep | lld:pubmed |
| pubmed-article:7453713 | pubmed:issn | 0027-5107 | lld:pubmed |
| pubmed-article:7453713 | pubmed:author | pubmed-author:GenerosoW MWM | lld:pubmed |
| pubmed-article:7453713 | pubmed:author | pubmed-author:GossleeD GDG | lld:pubmed |
| pubmed-article:7453713 | pubmed:author | pubmed-author:SheuC JCJ | lld:pubmed |
| pubmed-article:7453713 | pubmed:author | pubmed-author:NewellG WGW | lld:pubmed |
| pubmed-article:7453713 | pubmed:author | pubmed-author:BishopJ BJB | lld:pubmed |
| pubmed-article:7453713 | pubmed:author | pubmed-author:von HalleEE | lld:pubmed |
| pubmed-article:7453713 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:7453713 | pubmed:volume | 76 | lld:pubmed |
| pubmed-article:7453713 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:7453713 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:7453713 | pubmed:pagination | 191-215 | lld:pubmed |
| pubmed-article:7453713 | pubmed:dateRevised | 2007-11-15 | lld:pubmed |
| pubmed-article:7453713 | pubmed:meshHeading | pubmed-meshheading:7453713-... | lld:pubmed |
| pubmed-article:7453713 | pubmed:meshHeading | pubmed-meshheading:7453713-... | lld:pubmed |
| pubmed-article:7453713 | pubmed:meshHeading | pubmed-meshheading:7453713-... | lld:pubmed |
| pubmed-article:7453713 | pubmed:meshHeading | pubmed-meshheading:7453713-... | lld:pubmed |
| pubmed-article:7453713 | pubmed:meshHeading | pubmed-meshheading:7453713-... | lld:pubmed |
| pubmed-article:7453713 | pubmed:meshHeading | pubmed-meshheading:7453713-... | lld:pubmed |
| pubmed-article:7453713 | pubmed:meshHeading | pubmed-meshheading:7453713-... | lld:pubmed |
| pubmed-article:7453713 | pubmed:meshHeading | pubmed-meshheading:7453713-... | lld:pubmed |
| pubmed-article:7453713 | pubmed:meshHeading | pubmed-meshheading:7453713-... | lld:pubmed |
| pubmed-article:7453713 | pubmed:meshHeading | pubmed-meshheading:7453713-... | lld:pubmed |
| pubmed-article:7453713 | pubmed:meshHeading | pubmed-meshheading:7453713-... | lld:pubmed |
| pubmed-article:7453713 | pubmed:meshHeading | pubmed-meshheading:7453713-... | lld:pubmed |
| pubmed-article:7453713 | pubmed:meshHeading | pubmed-meshheading:7453713-... | lld:pubmed |
| pubmed-article:7453713 | pubmed:year | 1980 | lld:pubmed |
| pubmed-article:7453713 | pubmed:articleTitle | Heritable translocation test in mice. | lld:pubmed |
| pubmed-article:7453713 | pubmed:publicationType | Journal Article | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7453713 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7453713 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7453713 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7453713 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7453713 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:7453713 | lld:pubmed |
