Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1981-3-17
pubmed:abstractText
The advantages and the performance of PTFE reaction coils in photochemical reaction detectors for high-performance liquid chromatography (HPLC) are discussed. The excellent performance of these materials at irradiation wavelengths below 300 nm is based on a diffuse radiation transfer and an internal reflectance (light-tube) effect. Optimal coil designs can be obtained from signal vs. flow-rate curves for a particular application. Lamp performance has to be tested periodically and the reactor should be equipped with an efficient cooling system. Application of the principle to the fluorimetric detection of clobazam and phenothiazines after HPLC separation is discussed. The sensitive detection of these pharmaceuticals and their metabolites in serum with a minimum of sample handling demonstrates the potential of photochemical reaction detectors.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0021-9673
pubmed:author
pubmed:issnType
Print
pubmed:day
31
pubmed:volume
199
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
239-48
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1980
pubmed:articleTitle
Use of PTFE coils in post-column photochemical reactors for liquid chromatography--application to pharmaceuticals.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't