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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1981-3-24
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pubmed:abstractText |
The role of urine as a tumor-enhancing agent in urinary bladder carcinogenesis was investigated by using the heterotopically transplanted rat urinary bladder. Bladders removed from rats initiated with the carcinogen N-butyl-N-(4-hydroxybutyl)nitrosamine in drinking water for 4 or 10 weeks were heterotransplanted to syngeneic rats. These heterotopically transplanted bladders receiving repeated instillations of normal rat urine subsequent to transplantation had a higher incidence of carcinoma than did those receiving 0.9% NaCl solution. These results suggest that normal urine may contain tumor promoter(s).
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0008-5472
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
41
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
478-81
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:7448795-Animals,
pubmed-meshheading:7448795-Butylhydroxybutylnitrosamine,
pubmed-meshheading:7448795-Cocarcinogenesis,
pubmed-meshheading:7448795-Male,
pubmed-meshheading:7448795-Neoplasms, Experimental,
pubmed-meshheading:7448795-Rats,
pubmed-meshheading:7448795-Urinary Bladder Neoplasms,
pubmed-meshheading:7448795-Urine
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pubmed:year |
1981
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pubmed:articleTitle |
Enhancement by urine of urinary bladder carcinogenesis.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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