Linked Life Data

7448607

Source:http://linkedlifedata.com/resource/pubmed/id/7448607

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1981-3-24
pubmed:abstractText
Cerebrospinal fluid pressure (CSFP) by lumbar puncture, systemic blood pressure (BP) and pulse rate (PR) were measured for 15 minutes during the induction phase of general anaesthesia in seven groups of six healthy female patients each. Intravenous drugs, thiopentopne 5 mg . kg-1, alfathesin 50 microliters . kg-1 and diazepam 0.5 mg . kg-1 given in 10 to 20 seconds caused a fall of CSFP and BP, whereas ketamine 2 mg . kg-1 and a three-minute induction with halothane three per cent, trichloroethylene one per cent, or methoxyflurane 0.75 per cent caused a sharp highly significant but short-lived rise of CSFP. Unlike ketamine, trichlorethylene and methoxyflurane, halothane caused a simultaneous significant fall of BP. To rule out apprehension as the cause of the rise of CSFP with inhalation agents a second challenge was given with similar concentrations of the vapours while patients were asleep. These still produced a sharp and significant rise of CSFP.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0008-2856
pubmed:author
pubmed:issnType
Print
pubmed:volume
27
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
464-70
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1980
pubmed:articleTitle
Cerebrospinal fluid pressure changes during the induction phase of anaesthesia.
pubmed:publicationType
Journal Article