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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
1981-2-19
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pubmed:abstractText |
In order to determine if the diagnostic yield of the transbronchial lung biopsy in sarcoidosis is dependent upon the number of biopsies, a study was designed to examine individual specimens from 6 biopsies in patients with Stage II sarcoidosis. It was found that the probability of obtaining a positive specimen per biopsy was 46%, and this percentage remained constant for each biopsy. The diagnostic yield followed a logarithmic curve, gradually increasing from 1 through 4 biopsies until about 90% of true positive diagnoses were obtained, then approaching a plateau with successive biopsies. We therefore recommend that 4 transbronchial lung biopsies are sufficient to diagnose stage II sarcoidosis in the majority of patients with diffuse lung disease.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0003-0805
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
122
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
721-4
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:7447156-Adolescent,
pubmed-meshheading:7447156-Adult,
pubmed-meshheading:7447156-Biopsy,
pubmed-meshheading:7447156-Bronchoscopy,
pubmed-meshheading:7447156-Diagnosis, Differential,
pubmed-meshheading:7447156-Female,
pubmed-meshheading:7447156-Humans,
pubmed-meshheading:7447156-Lung,
pubmed-meshheading:7447156-Male,
pubmed-meshheading:7447156-Middle Aged,
pubmed-meshheading:7447156-Pulmonary Alveoli,
pubmed-meshheading:7447156-Sarcoidosis
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pubmed:year |
1980
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pubmed:articleTitle |
Transbronchial lung biopsy in sarcoidosis. An approach to determine the optimal number of biopsies.
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pubmed:publicationType |
Journal Article
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