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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1979-5-23
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pubmed:abstractText |
The distribution of alpha-melanocyte-stimulating hormone (alpha-MSH) was studied in the rat brain with an immunoperoxidase technique. alpha-MSH-containing cells were found in the arcuate nucleus of the hypothalamus. Cells staining for alpha-MSH were also localized in the intermediate lobe of the pituitary. alpha-MSH-containing nerve fibers extended throughout regions of the hypothalamus, thalamus, and midbrain. Two weeks after hypophysectomy, alpha-MSH-positive cells anf fibers were still present in the brain. These results indicate that alpha-MSH of non-pituitary origin is synthesized and stored by neural structures in the rat brain. The detection of alpha-MSH by radioimmunoassay in the rat brain and pituitary supports these observations.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0013-7227
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
102
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1283-91
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pubmed:dateRevised |
2005-11-17
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pubmed:meshHeading |
pubmed-meshheading:744026-Animals,
pubmed-meshheading:744026-Brain Chemistry,
pubmed-meshheading:744026-Histocytochemistry,
pubmed-meshheading:744026-Hypophysectomy,
pubmed-meshheading:744026-Hypothalamus,
pubmed-meshheading:744026-Male,
pubmed-meshheading:744026-Melanocyte-Stimulating Hormones,
pubmed-meshheading:744026-Mesencephalon,
pubmed-meshheading:744026-Nerve Fibers,
pubmed-meshheading:744026-Pituitary Gland,
pubmed-meshheading:744026-Radioimmunoassay,
pubmed-meshheading:744026-Rats,
pubmed-meshheading:744026-Thalamus
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pubmed:year |
1978
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pubmed:articleTitle |
Localization of alpha-melanocyte-stimulating hormone in rat brain and pituitary.
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pubmed:publicationType |
Journal Article
|