Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1979-5-16
pubmed:abstractText
Intraperitoneal administration of ketamine produced dose-dependent hypothermia at the ambient temperatures (Ta) of both 8 and 23 degrees C in unanesthetized rats. At a Ta of 8 degrees C, the hypothermia was brought about solely by a decrease in metabolic heat production. There were no changes in either the tail skin temperature (Ttail) or the sole skin temperature (Tsole). At a Ta of 23 degrees C, the hypothermia was due to an increase in Ttail, and increase in Tsole, and a decrease in metabolic heat production. However, at a Ta of 31 degrees C, there were no changes in rectal temperature in response to ketamine application, since neither heat production nor skin temperatures (e.g., Ttail and Tsole) was affected by ketamine at this Ta. The data indicate that the effect of the drug treatment may be to decrease heat production and (or) increase heat loss.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0008-4212
pubmed:author
pubmed:issnType
Print
pubmed:volume
56
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
963-7
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1978
pubmed:articleTitle
Effect of ketamine on thermoregulation in rats.
pubmed:publicationType
Journal Article