Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1981-1-29
pubmed:abstractText
The thick paw epidermis of the rat and the guinea pig showed a relatively increased amount of the heaviest fibrous polypeptide compared to the thinner epidermis of back and ear. The hyperplastic epidermis of mouse and rat induced by abrasion or painting with 12-0-tetra-decanoyl-phorbal-13-acetate (TPA) also revealed an increase in the heaviest polypeptide. The fibrous polypeptides of epidermis from scarred skin lacked components present in normal epidermis. Cultured epidermal cells showed a different fibrous polypeptide composition than the parent tissue which was altered when the cells were transplanted to an animal or grown on a dermal substrate in culture. Thus multiple factors such as hyperplasia, the dermis and cellular environment may modify the polypeptides synthesized by the keratinocyte.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0022-202X
pubmed:author
pubmed:issnType
Print
pubmed:volume
75
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
383-7
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1980
pubmed:articleTitle
Modification of polypeptide composition in keratinocyte fibrous protein.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, U.S. Gov't, P.H.S.