Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5 Suppl
pubmed:dateCreated
1981-1-26
pubmed:abstractText
Eight patients with hematologic malignant disease presented with associated alveolar proteinosis. All but one of these patients also had evidence of opportunistic infections. No explanation for this association could be elicited, but all patients appeared immunosuppressed at the time of their death. Autopsy revealed proteinaceous material or micro-organisms in the alveoli, but the inflammatory response was minimal. Forty cases of opportunistic infections and 22 cases of hematologic malignant disease were found among the patients with alveolar proteinosis reported in the literature. Lungs in these cases also lacked a significant number of inflammatory cells capable of phagocytosis. On the basis of these observations, a hypothesis is formulated to explain alveolar proteinosis as being a result of poor alveolar clearance in immunosuppressed patients.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0046-8177
pubmed:author
pubmed:issnType
Print
pubmed:volume
11
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
527-35
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1980
pubmed:articleTitle
Alveolar proteinosis as a consequence of immunosuppression. A hypothesis based on clinical and pathologic observations.
pubmed:publicationType
Journal Article