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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
1981-1-16
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pubmed:abstractText |
A strain of Chlamydia trachomatis isolated in McCoy cells from the urethra of a patient suffering from non-gonococcal urethritis was inoculated into the vagina of 8 female marmosets. Chlamydiae were isolated repeatedly for 10-42 days from the lower genital tract of 7 of the marmosets. Six of the infected animals developed an acute inflammatory reaction in the genital tract and chlamydial inclusions in epithelial cells were seen in smears from 2 of them. In addition, each of 6 infected marmosets examined developed humoral antibodies to C. trachomatis. In contrast, 3 control animals inoculated intravaginally with chlamydia-free McCoy cells showed no evidence of chlamydial infection. Since the marmoset is small and easily bred in captivity, it should provide a useful model for studying the mechanisms of chlamydial pathogenicity.
|
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Jun
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pubmed:issn |
0007-1021
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
61
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
291-5
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pubmed:dateRevised |
2003-11-14
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pubmed:meshHeading |
pubmed-meshheading:7426384-Animals,
pubmed-meshheading:7426384-Antibodies, Bacterial,
pubmed-meshheading:7426384-Callithrix,
pubmed-meshheading:7426384-Chlamydia Infections,
pubmed-meshheading:7426384-Chlamydia trachomatis,
pubmed-meshheading:7426384-Disease Models, Animal,
pubmed-meshheading:7426384-Epithelium,
pubmed-meshheading:7426384-Female,
pubmed-meshheading:7426384-Genital Diseases, Female,
pubmed-meshheading:7426384-Genitalia, Female
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pubmed:year |
1980
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pubmed:articleTitle |
Experimental infection of the marmoset genital tract with Chlamydia trachomatis.
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pubmed:publicationType |
Journal Article
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