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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
5
|
| pubmed:dateCreated |
1980-12-16
|
| pubmed:abstractText |
A technique for measuring focal cerebral blood flow (CBF) and brain specific gravity (SG) in gerbils is described; CO2 reactivity and autoregulation were tested. The mean CBF was 29.5 +/- 4.5 ml/100 gm/min and brain SG 1.0500 +/- 0.0004. Unilateral carotid occlusion resulted in a reduction of flow to 12.8 +/- 5.8 ml/100 gm/min in the ipsilateral hemisphere with little change in the contraleteral hemisphere; there was also a decrease in brain SG. One hour after occlusion, brain edema, as judged by decreased SG, developed at CBF less than 20 ml/100 gm/min and reached maximal levels at 7 +/- 2 ml/100 gm/min. The amount of edema appeared to be related chiefly to the residual post-occlusion flow. With bilateral occlusion, CBF was close to zero and there was no change in SG, indicating that in the "no flow" situation, there is no edema.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0039-2499
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
11
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
494-8
|
| pubmed:dateRevised |
2003-11-14
|
| pubmed:meshHeading |
pubmed-meshheading:7423581-Animals,
pubmed-meshheading:7423581-Arterial Occlusive Diseases,
pubmed-meshheading:7423581-Blood Pressure,
pubmed-meshheading:7423581-Brain Edema,
pubmed-meshheading:7423581-Carotid Arteries,
pubmed-meshheading:7423581-Cerebrovascular Circulation,
pubmed-meshheading:7423581-Gerbillinae,
pubmed-meshheading:7423581-Specific Gravity
|
| pubmed:articleTitle |
Cerebral blood flow and edema following carotid occlusion in the gerbil.
|
| pubmed:publicationType |
Journal Article
|