Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1980-12-18
pubmed:abstractText
After 2 and 7 days on n-octane and n-nonane administration (intraperitoneally) to female albino rats, alterations in the levels of hepatic xenobiotic metabolising enzyme activities and TBA reactants were observed. Fifty to eighty per cent reduction in the specific activities of benzo[a]pyrene hydroxylase, benzphetamine-N-demethylase, p-nitroanisole-O-demethylase and glutathione-S-transferase were observed. Cytochrome P-450 and free sulfhydryl contents of liver were also decreased significantly after 7 days treatment on n-octane and n-nonane. A 2- and 3- fold increase in liver lipid peroxidation estimated as TBA reactants was observed in the animals treated for 2 or 7 days with n-octane or n-nonane.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0300-483X
pubmed:author
pubmed:issnType
Print
pubmed:volume
16
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
239-45
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1980
pubmed:articleTitle
n-Octane and n-nonane induced alterations in xenobiotic metabolising enzyme activities and lipid peroxidation of rat liver.
pubmed:publicationType
Journal Article