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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
|
| pubmed:dateCreated |
1980-12-18
|
| pubmed:abstractText |
Alpha-bungarotoxin binding sites in chick retina from 12 days in ovo to hatching, were visualized at the ultrastructural level by use of a 1:1 conjugate of horseradish peroxidase with alpha-bungarotoxin. At all stages binding sites in the inner plexiform layer were localized in synapses, predominantly on or near the postsynaptic membrane. Localization of binding sites was found in bipolar and amacrine-cell synapses which appeared morphologically immature as well as in more well developed synapses. The results suggest that alpha-bungarotoxin-binding synapses, tentatively considered to be nicotinic cholinergic, are formed throughout the course of synaptogenesis, and that the aggregation of nicotinic receptors occurs early in the formation of these synapses.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Nov
|
| pubmed:issn |
0006-8993
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
10
|
| pubmed:volume |
201
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
45-56
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:7417840-Age Factors,
pubmed-meshheading:7417840-Animals,
pubmed-meshheading:7417840-Binding Sites,
pubmed-meshheading:7417840-Bungarotoxins,
pubmed-meshheading:7417840-Chick Embryo,
pubmed-meshheading:7417840-Chickens,
pubmed-meshheading:7417840-Microscopy, Electron,
pubmed-meshheading:7417840-Receptors, Nicotinic,
pubmed-meshheading:7417840-Retina,
pubmed-meshheading:7417840-Synapses
|
| pubmed:year |
1980
|
| pubmed:articleTitle |
Localization of alpha-bungarotoxin binding sites in synapses of the developing chick retina.
|
| pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't
|