Linked Life Data

7416848

Source:http://linkedlifedata.com/resource/pubmed/id/7416848

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1980-11-20
pubmed:abstractText
The energy producing reactions of spermatozoa will cease after the spermatozoa have been damaged by a complement-mediated antibody reaction and, consequently, their ATP content falls rapidly. The finding was applied and used for determination of the cytotoxic reaction caused by sperm antibodies. This reaction could be recorded by comparing the difference in ATP content between damaged and control spermatozoa after 2 hr incubation. A serum dilution that still reduced the ATP content by 50% or more was regarded to be cytotoxic. Only those sera, collected from infertile patients, with an agglutinating titer of at lease 1:64 and an immobilizing titer of 1:4 were cytotoxic to spermatozoa. The method proved to be both simple and more sensitive than the supraviatal staining technique as a cytotoxicity test.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0148-5016
pubmed:author
pubmed:issnType
Print
pubmed:volume
4
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
257-64
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1980
pubmed:articleTitle
A new method for measurement of cytotoxic antibodies to human spermatozoa.
pubmed:publicationType
Journal Article