Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1980-11-25
pubmed:abstractText
Corneal perforation and withdrawal of aqueous humor (paracentesis) represents a practical means for producing controlled trauma to the eye. The sequence of events triggered by paracentesis has been carefully studied by in vivo and in vitro microscopy and other means. These observations have proven especially helpful in elucidating the physiology and pharmacology of ocular trauma. Scanning electron microscopy of the ciliary processes of the rabbit has proven a sensitive indicator of the response to prostaglandin, a mediator of the paracentesis reaction. We used SEM to invetigate changes in the ciliary processes induced by paracentesis. We also examined the opposite eye for a consensual response. The effect of prior treatment with aspirin or nerve block was assessed in both the traumatized eye and the fellow eye. In an untreated animal, a consensual response to trauma was present and demonstrable by scanning electron microscopy. The direct response was more effectively blocked by aspirin than by local anesthesia. Both pretreatments were effective in reducing the consensual reaction.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0586-5581
pubmed:author
pubmed:issnType
Print
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
441-7
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1980
pubmed:articleTitle
SEM of the ciliary processes after paracentesis.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.