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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1980-11-24
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pubmed:abstractText |
Conjunctivitis follicularis is characterized by the appearance of cellular infiltrates consisting of lymphocytes, eosinophils and mast cells; this has led to the assumption of an allergic etiology in many cases. In a first attempt to prove this hypothesis three cases of conjunctivitis follicularis were investigated using the following immunological methods: (1) determination of immunoglobulins in the lacrimal fluid by means of quantitative precipitation (IgG, IgA, IgM), and by a direct radioimmunoassay for IgE; (2) direct immunofluorescence test on cryostat sections of biopsy specimens of diseased conjunctiva to detect immunoglobulin-producing plasma cells. According to initial results the infiltrated conjunctiva contains considerable numbers of plasma cells producing mainly IgA, and IgM. Plasma cells positively stained with anti-IgG and notably with anti-IgE were only rarely found. These findings, which were also supported by the quantitative Ig determinations in the lacrimal fluids, tend to rule out an allergic, IgE-mediated pathomechanism in these cases.
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pubmed:language |
ger
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Immunoglobulin A,
http://linkedlifedata.com/resource/pubmed/chemical/Immunoglobulin E,
http://linkedlifedata.com/resource/pubmed/chemical/Immunoglobulin G,
http://linkedlifedata.com/resource/pubmed/chemical/Immunoglobulin M,
http://linkedlifedata.com/resource/pubmed/chemical/Immunoglobulins
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0023-2165
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
176
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
70-5
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pubmed:dateRevised |
2009-11-11
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pubmed:meshHeading |
pubmed-meshheading:7412169-Adult,
pubmed-meshheading:7412169-Child,
pubmed-meshheading:7412169-Conjunctivitis,
pubmed-meshheading:7412169-Humans,
pubmed-meshheading:7412169-Immunoglobulin A,
pubmed-meshheading:7412169-Immunoglobulin E,
pubmed-meshheading:7412169-Immunoglobulin G,
pubmed-meshheading:7412169-Immunoglobulin M,
pubmed-meshheading:7412169-Immunoglobulins,
pubmed-meshheading:7412169-Male,
pubmed-meshheading:7412169-Retina,
pubmed-meshheading:7412169-Tears
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pubmed:year |
1980
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pubmed:articleTitle |
[Immunological studies on conjunctivitis follicularis].
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pubmed:publicationType |
Journal Article,
English Abstract,
Case Reports
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