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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
1980-11-20
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pubmed:abstractText |
Within minutes of CTL-target interaction, the intracellular disintegration of the target cell nucleus begins. This nuclear event satisfies the ionic and temperature requirements that have been described by others as important in CTL-mediated lysis. Such nuclear disintegration does not occur in Ab+C-lysed targets. Thus the target cell nucleus appears to signal a primary event in CTL-mediated lysis that distinguishes the CTL lytic mechanism from that of Ab+C.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0022-1767
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
125
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1256-61
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:7410838-Animals,
pubmed-meshheading:7410838-Antibodies,
pubmed-meshheading:7410838-Calcium,
pubmed-meshheading:7410838-Cell Communication,
pubmed-meshheading:7410838-Cell Nucleus,
pubmed-meshheading:7410838-Complement System Proteins,
pubmed-meshheading:7410838-Cytotoxicity, Immunologic,
pubmed-meshheading:7410838-Magnesium,
pubmed-meshheading:7410838-Mice,
pubmed-meshheading:7410838-Mice, Inbred BALB C,
pubmed-meshheading:7410838-Mice, Inbred C57BL,
pubmed-meshheading:7410838-Mice, Inbred DBA,
pubmed-meshheading:7410838-Polyethylene Glycols,
pubmed-meshheading:7410838-Rabbits,
pubmed-meshheading:7410838-Solubility,
pubmed-meshheading:7410838-Time Factors,
pubmed-meshheading:7410838-Uridine
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pubmed:year |
1980
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pubmed:articleTitle |
Mechanisms of immune lysis. II. CTL-induced nuclear disintegration of the target begins within minutes of cell contact.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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