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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2-3
|
| pubmed:dateCreated |
1980-11-24
|
| pubmed:abstractText |
An application of decision theory to the design of phase II clinical trials in cancer is presented. A risk function which depends on the prior distribution of the response rate, the costs of treating a patient, and the gains or losses resulting from the decision taken upon completion of the study is derived and optimal restricted sampling plans for a response rate of 20% are provided.
|
| pubmed:grant | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0361-5960
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
64
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
519-24
|
| pubmed:dateRevised |
2007-11-14
|
| pubmed:meshHeading |
pubmed-meshheading:7407793-Decision Theory,
pubmed-meshheading:7407793-Drug Evaluation,
pubmed-meshheading:7407793-Humans,
pubmed-meshheading:7407793-Models, Biological,
pubmed-meshheading:7407793-Neoplasms,
pubmed-meshheading:7407793-Research Design,
pubmed-meshheading:7407793-Risk,
pubmed-meshheading:7407793-Sampling Studies
|
| pubmed:articleTitle |
Design of phase II clinical trials in cancer using decision theory.
|
| pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
|