Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1979-4-25
pubmed:abstractText
A radioimmunoassay is described for the measurement of tobramycin in serum or plasma. The technique has advantages over other assay techniques with regard to precision, specificity, sensitivity and rapidity. The radioimmunoassay uses a tracer labelled with 125Iodine. The iodination technique is simple and gives tracer in high yield, at high specific activity and with complete immunological identity to unlabelled tobramycin. There is a significant correlation between the results obtained by this radioimmunoassay and by the disc-plate assay. Such knowledge of serum levels of tobramycin assists the clinician in regulating drug dosage to obtain an optimum therapeutic effect, and yet avoids toxic serum levels.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0031-3025
pubmed:author
pubmed:issnType
Print
pubmed:volume
10
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
307-15
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1978
pubmed:articleTitle
Radioimmunoassay for serum tobramycin levels using 125I-labeled tobramycin.
pubmed:publicationType
Journal Article, Comparative Study