Linked Life Data

7402269

Source:http://linkedlifedata.com/resource/pubmed/id/7402269

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
13
pubmed:dateCreated
1980-10-27
pubmed:abstractText
Immunologic causes of infertility have been postulated for many years, but a precise means for identification of men or women with antibodies against sperm has not been available. We studied 614 patients, including 257 couples, with unexplained in fertility, to detect the presence of circulating antisperm antibody. Using a specific radiolabeled-antiglobulin test, we identified a subset of patients (10 per cent) with IgG antisperm antibody; this antibody was present in 13 per cent of the women and 7 per cent of the men. We followed the course of six infertile couples in whom one partner had sperm antibody. In four couples, pregnancy was achieved; pregnancy correlated with resolution of antibody activity. In two of these four couples the partner (one man and one woman) with antisperm activity had been pretreated with corticosteroids. We conclude that this objective test may be used to identify and then to help manage infertility in patients with suspected antibody-mediated infertility.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0028-4793
pubmed:author
pubmed:issnType
Print
pubmed:day
25
pubmed:volume
303
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
722-7
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1980
pubmed:articleTitle
Immunologic infertility: identification of patients with antisperm antibody.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.