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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2
|
| pubmed:dateCreated |
1980-10-24
|
| pubmed:abstractText |
The inhibitory effects of beta-sitosterol on intestinal cholesterol absorption were studied by means of a dual isotope plasma ratio method (in vivo), which is a new technique for the measurement of cholesterol absorption, as well as a ligated-loop method (in situ). The results obtained were as follows: 1. The absorption of beta-sitosterol itself was significantly less than cholesterol. Cholesterol was selectively absorbed from rat intestine. 2. When 100 to 1,000 microgram of beta-sitosterol were added to the dose solution containing 10 microgram of cholesterol, cholesterol absorption by the in vivo experiment decreased with the increae of additional beta-sitosterol. 3. A similar inhibitory effect of beta-sitosterol was observed by the in situ ligated-loop method. These results suggest that beta-sitosterol actually inhibits cholesterol absorption in the physiological state of an animal.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0301-4800
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
26
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
183-8
|
| pubmed:dateRevised |
2003-11-14
|
| pubmed:meshHeading |
pubmed-meshheading:7400864-Animals,
pubmed-meshheading:7400864-Carbon Radioisotopes,
pubmed-meshheading:7400864-Cholesterol,
pubmed-meshheading:7400864-Intestinal Absorption,
pubmed-meshheading:7400864-Intestinal Mucosa,
pubmed-meshheading:7400864-Rats,
pubmed-meshheading:7400864-Sitosterols,
pubmed-meshheading:7400864-Tritium
|
| pubmed:year |
1980
|
| pubmed:articleTitle |
Inhibition of beta-sitosterol on intestinal cholesterol absorption in rat using in vivo dual isotope ratio method.
|
| pubmed:publicationType |
Journal Article
|