pubmed-article:7399697 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:7399697 | lifeskim:mentions | umls-concept:C0332307 | lld:lifeskim |
pubmed-article:7399697 | lifeskim:mentions | umls-concept:C0034693 | lld:lifeskim |
pubmed-article:7399697 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
pubmed-article:7399697 | lifeskim:mentions | umls-concept:C0724668 | lld:lifeskim |
pubmed-article:7399697 | lifeskim:mentions | umls-concept:C1178694 | lld:lifeskim |
pubmed-article:7399697 | pubmed:issue | 3 | lld:pubmed |
pubmed-article:7399697 | pubmed:dateCreated | 1980-10-24 | lld:pubmed |
pubmed-article:7399697 | pubmed:abstractText | The response to type 3 pneumococcal polysaccharide vaccination, the protective effect of type 3 pneumococcal polysaccharide vaccination, and the ability of hemagglutinating antibody to type 3 pneumococcal polysaccharide to cross the blood-brain barrier were studied in rats. Hemagglutinating antibody response to vaccination with type 3 pneumococcal polysaccharide was found to be dependent on the dose and route of inoculation. Intraperitoneal vaccination with type 3 pneumococcal polysaccharide protected the rats from subsequent intraperitoneal challenge with type 3 Streptococcus pneumoniae but had no effect after intracisternal challenge with type 3 S. pneumoniae. In the presence or absence of sterile meningeal inflammation, hemagglutinating antibody could not be found in cerebrospinal fluid of animals vaccinated intraperitoneally with type 3 pneumococcal polysaccharide. These results suggest that type 3 pneumococcal polysaccharide is antigenic in rats and intraperitoneal vaccination with type 3 pneumococcal polysaccharide does not protect against experimental meningitis because antibodies do not cross the blood-brain barrier. | lld:pubmed |
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pubmed-article:7399697 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
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pubmed-article:7399697 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:7399697 | pubmed:language | eng | lld:pubmed |
pubmed-article:7399697 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:7399697 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:7399697 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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pubmed-article:7399697 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:7399697 | pubmed:month | Jun | lld:pubmed |
pubmed-article:7399697 | pubmed:issn | 0019-9567 | lld:pubmed |
pubmed-article:7399697 | pubmed:author | pubmed-author:ClarkG MGM | lld:pubmed |
pubmed-article:7399697 | pubmed:author | pubmed-author:HodgesG RGR | lld:pubmed |
pubmed-article:7399697 | pubmed:author | pubmed-author:DegenerC ECE | lld:pubmed |
pubmed-article:7399697 | pubmed:author | pubmed-author:WorleyS ESE | lld:pubmed |
pubmed-article:7399697 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:7399697 | pubmed:volume | 28 | lld:pubmed |
pubmed-article:7399697 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:7399697 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:7399697 | pubmed:pagination | 832-6 | lld:pubmed |
pubmed-article:7399697 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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pubmed-article:7399697 | pubmed:meshHeading | pubmed-meshheading:7399697-... | lld:pubmed |
pubmed-article:7399697 | pubmed:year | 1980 | lld:pubmed |
pubmed-article:7399697 | pubmed:articleTitle | Antigenicity and protective effects of type 3 pneumococcal polysaccharide in rats. | lld:pubmed |
pubmed-article:7399697 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:7399697 | pubmed:publicationType | Research Support, U.S. Gov't, Non-P.H.S. | lld:pubmed |
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