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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1980-10-21
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pubmed:abstractText |
Prolactin has been suggested to exert a diabetogenic action in animal and man. Thus this report is concerned with the changes of serum prolactin in severely hyperglycaemic patients in a praecomatous state (n = 12). Basal serum prlactin levels were 12.0 +/- 3.4 (SE) ng/ml on admission and well within the normal range (less than 20 ng/ml). Rehydration of the patients which induced a significant fall in blood glucose (31.2 +/- 2.1 to 21.6 +/- 2.9 mmol/l) and in serum osmolality (336 +/- 9 to 316 +/- 10 mosmol/kg H2O) was however without any effect in serum prolactin concentration (9.9 +/- 2.5 ng/ml at the end of the rehydration period). We conclude that prolactin is not involved in the severe endocrine and metabolic derangements seen in diabetic praecoma; its secretion does not seem to be markedly altered by acute changes in blood glucose and serum osmolality.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0013-7251
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
75
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
235-9
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:7398593-Adolescent,
pubmed-meshheading:7398593-Adult,
pubmed-meshheading:7398593-Aged,
pubmed-meshheading:7398593-Blood Glucose,
pubmed-meshheading:7398593-Diabetic Coma,
pubmed-meshheading:7398593-Epinephrine,
pubmed-meshheading:7398593-Female,
pubmed-meshheading:7398593-Fluid Therapy,
pubmed-meshheading:7398593-Humans,
pubmed-meshheading:7398593-Male,
pubmed-meshheading:7398593-Middle Aged,
pubmed-meshheading:7398593-Norepinephrine,
pubmed-meshheading:7398593-Osmolar Concentration,
pubmed-meshheading:7398593-Prolactin
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pubmed:year |
1980
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pubmed:articleTitle |
Prolactin in diabetic praecoma.
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pubmed:publicationType |
Journal Article
|