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rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
3
|
|
pubmed:dateCreated |
1980-9-23
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|
pubmed:abstractText |
The pathways of ammonia neutralization in the rat heart muscle were traced with nitrogen-15 isotope. The effect of ammonia concentration in the perfusate on its utilization by the myocardium was investigated over the range of 1.6--3.4 mM. Considerable amounts of the neutralized ammonia were found in glutamine and glutamic acid, less quantities in alanine and aspartic acid. Isoproterenol-induced necrosis of the heart muscle leads to a decrease in both glutamine and alanine ability to bind ammonia (20--40 and 30--45%, respectively). The necrosis effect is not significant for glutamic acid. In necrosis nitrogen-15 incorporation into aspartic acid declines whereas with higher concentrations it significantly increases.
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|
pubmed:language |
rus
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Mar
|
|
pubmed:issn |
0365-9615
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
89
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
289-91
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|
pubmed:dateRevised |
2008-10-8
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|
pubmed:meshHeading |
pubmed-meshheading:7388135-Alanine,
pubmed-meshheading:7388135-Ammonia,
pubmed-meshheading:7388135-Animals,
pubmed-meshheading:7388135-Aspartic Acid,
pubmed-meshheading:7388135-Cardiomyopathies,
pubmed-meshheading:7388135-Glutamates,
pubmed-meshheading:7388135-Glutamine,
pubmed-meshheading:7388135-Isoproterenol,
pubmed-meshheading:7388135-Male,
pubmed-meshheading:7388135-Myocardium,
pubmed-meshheading:7388135-Necrosis,
pubmed-meshheading:7388135-Rats
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|
pubmed:year |
1980
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|
pubmed:articleTitle |
[Neutralization of ammonia in cardiac muscle].
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|
pubmed:publicationType |
Journal Article,
English Abstract
|
