Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1980-8-25
pubmed:abstractText
Studies are made of the pH-induced intramolecular structuring of such random copolymers as glutamic acid with leucine. It is shown that these copolymers, consisting of hydrophobic and hydrophilic residues, contain large amounts of fractions capable of acquiring non-aggregating compact structures in aqueous medium. These fractions have an approximately similar amino acid composition which does not almost depend on the composition of the initial copolymers. A decrease in the degree of ionization of side groups of glutamic acid promotes a formation of helical regions in the molecules of these fractions. At a further deionization, the helical regions collapse into compact structures stabilized by hydrophobic interactions of side groups of leucine. The compactness of the obtained structures is close to that of protein globules.
pubmed:language
rus
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0026-8984
pubmed:author
pubmed:issnType
Print
pubmed:volume
14
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
278-86
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:articleTitle
[Compact structure of random copolymers of hydrophobic and hydrophilic amino acid residues].
pubmed:publicationType
Journal Article, English Abstract