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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
1980-8-15
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pubmed:abstractText |
Severe weakness of lower cranial and girdle muscles has been found in 4 subjects among 20 dialysis patients treated with carnitine in order to correct their high plasma triglyceride level. Neurophysiological investigation showed an impairment of neuromuscular transmission with short-term reduction of evoked muscle responses to repetitive stimulation and the presence of "post-activation exhaustion phenomenon" 3 min after the train. Both the weakness and the neurophysiological findings were less pronounced after edrophonium. These findings suggest a hemicholinium activity of carnitine at synaptic level.
|
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0022-510X
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
46
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
365-71
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:7381520-Adult,
pubmed-meshheading:7381520-Carnitine,
pubmed-meshheading:7381520-Edrophonium,
pubmed-meshheading:7381520-Electrophysiology,
pubmed-meshheading:7381520-Humans,
pubmed-meshheading:7381520-Middle Aged,
pubmed-meshheading:7381520-Muscular Diseases,
pubmed-meshheading:7381520-Neural Conduction,
pubmed-meshheading:7381520-Peripheral Nerves,
pubmed-meshheading:7381520-Renal Dialysis
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pubmed:year |
1980
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pubmed:articleTitle |
Myasthenia due to carnitine treatment.
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pubmed:publicationType |
Journal Article
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