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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1980-8-25
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pubmed:abstractText |
BN-183B is a new antitumor antibiotic with chlorine in its molecule found in the culture broth of Pseudomonas sp. BN-183. The compound was weakly basic and isolated as a hydrochloride in a pure state. The molecular formula of its free base was determined as C14H20N2O6Cl2. The antibiotic showed not only strong antimicrobial activity against both Gram-positive and Gram-negative bacteria but also marked activity toward experimental tumors such as lymphoid leukemia L-1210 and lymphocytic leukemia P-388 in mice. No mutagenicity of BN-183B was noted.
|
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
|
pubmed:issn |
0021-8820
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
33
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
|
pubmed:pagination |
213-20
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:7380731-Animals,
pubmed-meshheading:7380731-Antibiotics, Antineoplastic,
pubmed-meshheading:7380731-Benzopyrans,
pubmed-meshheading:7380731-Chemistry, Physical,
pubmed-meshheading:7380731-Lethal Dose 50,
pubmed-meshheading:7380731-Mice,
pubmed-meshheading:7380731-Mutagens,
pubmed-meshheading:7380731-Physicochemical Phenomena,
pubmed-meshheading:7380731-Pseudomonas,
pubmed-meshheading:7380731-Time Factors
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pubmed:year |
1980
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pubmed:articleTitle |
BN-183B, a new antitumor antibiotic produced by Pseudomonas. Taxonomy, isolation, physico-chemical and biological properties.
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pubmed:publicationType |
Journal Article
|