Linked Life Data

7380360

Source:http://linkedlifedata.com/resource/pubmed/id/7380360

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1980-8-15
pubmed:abstractText
Mechanisms of hepatic bile secretion were studied in unanesthetized bile fistula rats. After implantation of bile fistula, bile flow and bile acids secretion were significantly decreased and secondary bile acids were greatly decreased. After cholic acid (CA) 30 microM/100 g/hr infusion, bile juice was greatly increased, and CA was dramatically increased in bile. Biliary bile flow and bile acid were not increased after infusion of CDCA 30 microM/100 g/hr. CDCA was slightly increased in bile, but the amount of bile acids tended to decrease. DHCA dramatically increased the amount of bile juice, while DHCA was not detected in the bile. After DHCA infusion, 3 alpha, 7 alpha-dihydroxy-12-keto-5 beta-cholanic acid dramatically increased and slightly increased in CA. Regarding the relationship between the bile flow rate and the secretion rate of the total bile acids, bile acid-dependent bile secretion varied with the bile acid value. On the other hand, Na+ and K+ concentrations of bile were not related to bile acid concentration. These studies show that canalicular bile secretion mechanisms varied with the compositions of bile acids and bile acid secretion rate.
pubmed:language
jpn
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0015-5691
pubmed:author
pubmed:issnType
Print
pubmed:volume
76
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
25-32
pubmed:dateRevised
2011-7-27
pubmed:meshHeading
pubmed:year
1980
pubmed:articleTitle
[Choleretica properties of chenodeoxycholic acid CDCA and dehydrocholic acid (DHCA) in rats (author's transl)].
pubmed:publicationType
Journal Article, English Abstract