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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
|
pubmed:dateCreated |
1980-7-12
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pubmed:abstractText |
Thirty-two male social drinkers were arranged into two tolerance groups, based on changes in standing stability after ingestion of alcohol. Subjects consumed either a large (1.0 g/kg) or small (0.5 g/kg) dose of alcohol. On finishing their drinks, subjects were requested to interact with a female confederate whose continued silence induced anxiety. Heart rate, skin conductance, overt behavior, and self-report measures were taken. Heart rate increased more at the small than the large dose, consistent with the tension-reduction hypothesis. Further, heart rate of high-tolerance subjects increased significantly more than that of low-tolerance subjects, which suggests that alcohol was less effective at tension reduction for the high-tolerance group. Finally, measures of both skin conductance and heart rate showed significant dose-by-tolerance interactions. High-tolerance subjects were more aroused than were low-tolerance subjects at the small but not at the large dose, suggesting that high-tolerance subjects must consume more alcohol to achieve the same autonomic effect experienced by the low-tolerance subjects.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
May
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pubmed:issn |
0003-990X
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
37
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
577-82
|
pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:7377915-Adolescent,
pubmed-meshheading:7377915-Adult,
pubmed-meshheading:7377915-Alcohol Drinking,
pubmed-meshheading:7377915-Anxiety,
pubmed-meshheading:7377915-Dose-Response Relationship, Drug,
pubmed-meshheading:7377915-Drug Tolerance,
pubmed-meshheading:7377915-Ethanol,
pubmed-meshheading:7377915-Heart Rate,
pubmed-meshheading:7377915-Humans,
pubmed-meshheading:7377915-Male,
pubmed-meshheading:7377915-Postural Balance,
pubmed-meshheading:7377915-Pulse,
pubmed-meshheading:7377915-Social Behavior
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pubmed:year |
1980
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pubmed:articleTitle |
Effects of tolerance on the anxiety-reducing function of alcohol.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
|