Linked Life Data

7376260

Source:http://linkedlifedata.com/resource/pubmed/id/7376260

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1980-7-22
pubmed:abstractText
There seem to be some similarities between mechanisms employed by embryos and cancer cells from the maternal or tumor bearer's immune system. In the present study, we investigated the presence of hemagglutinins on placental cells and their relationship to circulating antibodies in mice immunized against sheep erythrocytes before mating. The results obtained demonstrated that placental cells may fix large quantities of maternal immunoglobulins. The hemagglutinins are probably fixed on placental cells by the Fc, since the combining sites of the antibody were free and able to react with the antigen in the "rosette" test. It was also demonstrated that placental tissue may fix up to 1/4 of the maternal circulating antibodies, while only 1/200 of them were transmitted to the fetuses. Some theoretical implications of the presence in the placenta of antibodies not directed against feto-placental antigens are also discussed.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0300-8916
pubmed:author
pubmed:issnType
Print
pubmed:volume
66
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1-12
pubmed:dateRevised
2008-12-12
pubmed:meshHeading
pubmed:year
1980
pubmed:articleTitle
Non-specifically bound immunoglobulins on mouse placental cells.
pubmed:publicationType
Journal Article