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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
|
pubmed:dateCreated |
1979-4-25
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pubmed:abstractText |
Cefuroxime, a new antibiotic derived from cephalosporin-C which is very stable in the presence of beta-lactamases produced by Gram-negative organisms, was used to treat 856 male patients and 340 female patients with uncomplicated gonorrhoea. In men the drug was used in three different doses, 1.5 g, 1 g, and 750 mg plus 1 g probenecid; in women 1 g and 750 mg cefuroxime plus 1 g probenecid was used. Cure rates ranged from 94.8% to 99.3%. The antibiotic was well tolerated and was free from side effects. Cefuroxime would be a valuable and efficient substitute for penicillin in the treatment of gonorrhoea due to beta-lactamase-producing strains of gonococci.
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pubmed:commentsCorrections | |
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Dec
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pubmed:issn |
0007-134X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
54
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
|
pubmed:pagination |
400-2
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:737517-Cephalosporins,
pubmed-meshheading:737517-Drug Administration Schedule,
pubmed-meshheading:737517-Drug Therapy, Combination,
pubmed-meshheading:737517-Female,
pubmed-meshheading:737517-Furans,
pubmed-meshheading:737517-Gonorrhea,
pubmed-meshheading:737517-Humans,
pubmed-meshheading:737517-Male,
pubmed-meshheading:737517-Probenecid
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pubmed:year |
1978
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pubmed:articleTitle |
Clinical experience in the use of cefuroxime in gonorrhoea.
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pubmed:publicationType |
Journal Article
|