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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
1980-7-26
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pubmed:abstractText |
Between 1961 and 1979, 349 patients with autonomously functioning thyroid nodules (AFTN) were seen. There were 287 nontoxic and 62 toxic lesions. Toxic lesions were seen in 56.5% of AFTN patients over 60 yr of age but in only 12.5% of the younger patients. The female to male ratio was 14.9:1 for nontoxic AFTN patients but only 5.9:1 for toxic AFTN patients. The proportion of toxic AFTN in patients less than 20 yr old (13.8%) was not significantly different from that in patients 20--60 yr old (12.7%). T3 toxicosis was observed in 46% of those patients with hyperthyroidism. All but 4 of the toxic AFTN measured 3 cm in diameter or larger. AFTN 3 cm or larger were more than twice as common in patients 40 yr or older than in younger patients. Of 159 untreated nontoxic AFTN patients, 14 became toxic within 1--6 yr. One patient in 5 with a nontoxic AFTN 3 cm or larger developed toxicity.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0021-972X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
50
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1089-93
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:7372787-Adolescent,
pubmed-meshheading:7372787-Adult,
pubmed-meshheading:7372787-Age Factors,
pubmed-meshheading:7372787-Aged,
pubmed-meshheading:7372787-Child,
pubmed-meshheading:7372787-Female,
pubmed-meshheading:7372787-Follow-Up Studies,
pubmed-meshheading:7372787-Humans,
pubmed-meshheading:7372787-Male,
pubmed-meshheading:7372787-Middle Aged,
pubmed-meshheading:7372787-Sex Factors,
pubmed-meshheading:7372787-Thyroid Diseases,
pubmed-meshheading:7372787-Triiodothyronine
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pubmed:year |
1980
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pubmed:articleTitle |
Evolution of toxicity in solitary nontoxic autonomously functioning thyroid nodules.
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pubmed:publicationType |
Journal Article
|