Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1980-6-16
pubmed:abstractText
Biopsies of hum endocervix were obtained from healthy women at day 5, 15, and 25 of the menstrual cycle, and immediately incubated with 3H-thymidine in a culture medium for 1 to 2 h. A few labelled nuclei were found in thick, semi-thin, and ultra-thin sections and indicated that gland cells of the columnar epithelium of the endocervix were capable of DNA synthesis and hence mitosis, independent of the menstrual cycle. As basal or "reserve" cells were less frequently labelled than differentiated epithelial cells, the findings suggested renewal of the secretory epithelium of the endocervix without cell replacement by basal or "reserve" cells. We discuss the implications of the results for the understanding of normal and neoplastic regeneration and for the treatment of cancer.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0170-9925
pubmed:author
pubmed:issnType
Print
pubmed:volume
229
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
83-90
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1980
pubmed:articleTitle
Regeneration of secretory epithelium in the human endocervix.
pubmed:publicationType
Journal Article