Linked Life Data

7366737

Source:http://linkedlifedata.com/resource/pubmed/id/7366737

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5757
pubmed:dateCreated
1980-6-16
pubmed:abstractText
In 1977, a unique event occurred in the epidemiology of influenza when a virus of the influenza A (H1N1) subtype, similar to a virus that had occurred in 1950, reappeared and caused worldwide epidemics but did not replace the prevailing influenza A (H2N2) subtype. Consequently, the two viruses co-circulated throughout the world and mixed infection of some individuals with both virus strains was detected, raising the possiblitity that recombination between the two strains might affect the future epidemiological behaviour of influenza. Serological analysis of virus isolates from influenza outbreaks during the winter of 1978-79, however, failed to detect any antigenic hybrids (H2N1 or H1N2). The investigation described here, was therefore, undertaken to detect recombinants among recent isolates of the H1N1 and H3N1 serotypes, involving genes coding for other than the surface proteins by RNA-RNA hybridisation. We report here the genetic characterisation of recombinants of both antigenic types.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0028-0836
pubmed:author
pubmed:issnType
Print
pubmed:day
17
pubmed:volume
284
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
638-40
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1980
pubmed:articleTitle
Recombination of human influenza A viruses in nature.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.