Linked Life Data

7364148

Source:http://linkedlifedata.com/resource/pubmed/id/7364148

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1980-6-16
pubmed:abstractText
We studied the influence of sex hormones using the hormone-sensitive levator ani muscle as a model tissue and glucose-6-phosphate dehydrogenase as an indicator of hormone action. Injection of testosterone or estradiol cause a 50% increase in the specific activity of glucose-6-phosphate dehydrogenase. The effect was dose-dependent, and was maximal at a dose of 2.5mg/100g body weight. Estradiol increased glucose-6-phosphate dehydrogenase as early as 8 h after injection, while testosterone required 12 h. Injection of estradiol on 2 successive days increased enzyme activity by 80%. The effect of estradiol was abolished by actinomycin D, suggesting enzyme induction. The results indicate a direct effect of estrogen on striated muscle.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0303-7207
pubmed:author
pubmed:issnType
Print
pubmed:volume
17
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
111-8
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1980
pubmed:articleTitle
Effect of sex hormones on glucose-6-phosphate dehydrogenase in rat levator ani muscle.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.