Linked Life Data

7363170

Source:http://linkedlifedata.com/resource/pubmed/id/7363170

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1980-6-16
pubmed:abstractText
Cations and trace metals play important roles in the pathophysiology of myocardium, and understanding their changes during cardioplegia may be important in further refining the technique of myocardial protection. Serial myocardial, blood and urine samples were taken from 12 patients undergoing cardiac operation under cold cardioplegia. The concentrations of calcium, magnesium, zinc and copper were measured with an atomic absorption spectrometer. Myocardial magnesium levels were found to be significantly (P less than 0.05) depleted when the "cardioplegic" solution contained 0.69 mmol/l of magnesium, but this could be prevented by increasing the magnesium concentration of the infusate to 2.2 mmol/l. With calcium-free infusate, the myocardial calcium concentration decreased, but zinc and copper values did not change significantly. There were decreased serum concentrations of these cations and trace metals during tbe hemodilution cardiopulmonary bypass but their 24-hour excretions in urine were within normal range. Although the clinical importance of such changes remains to be elucidated, the information may be valuable in designing future cardioplegic solutions with optimal compositions.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0008-428X
pubmed:author
pubmed:issnType
Print
pubmed:volume
23
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
113-6
pubmed:dateRevised
2007-8-16
pubmed:meshHeading
pubmed:year
1980
pubmed:articleTitle
Myocardial cations and trace metals in cardioplegia: a clinical study.
pubmed:publicationType
Journal Article