Linked Life Data

7361273

Source:http://linkedlifedata.com/resource/pubmed/id/7361273

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1980-5-14
pubmed:abstractText
The effect of anesthesia and laparotomy on the distribution of blood flow to the different tissue layers of the stomach, small bowel, and colon of the dog was studied using a double-isotope, microsphere technique. In conscious dogs total jejunal flow significantly exceeded both ileal and colonic flow. Mucosal flow comprised about two thirds of total gastric and small bowel flow, but less than half of colonic flow. Fifteen minutes after induction of anesthesia, there was a marked increase in flow to all levels of the alimentary tract, as well as to each tissue layer. This increase was transient, since by 1 hour flow to all gut levels had decreased nearly to baseline levels. Laparotomy per se did not significantly alter blood flow to the full thickness or mucosal layer of either stomach, small bowel, or colon. These findings indicate that future studies of gut function or blood flow should be performed in conscious animals or in anesthetized animals only after complete cardiovascular stabilization. Neither laparotomy nor anesthesia caused a redistrubtion of flow away from the mucosal layers, and hence the observation that patients have often stopped bleeding at the time of operation for uncontrolled hemorrhage is unexplained.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0039-6060
pubmed:author
pubmed:issnType
Print
pubmed:volume
87
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
313-8
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1980
pubmed:articleTitle
The effect of anesthesia and laparotomy on blood flow to the stomach, small bowel, and colon of the dog.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.